Fundamental Immunology [精裝] (基礎免疫學)

內容簡介

This standard-setting textbook has defined the field of immunology since 1984, and is now in its Seventh Edition continuing to deliver the detailed, authoritative, and timely coverage readers expect. This comprehensive, up-to-date text is ideal for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role.

Now full-color throughout the book's fully revised and updated content reflects the latest advances in the field. Current insights enhance readers' understanding of immune system function. The text's unique approach bridges the gap between basic immunology and the disease process. Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. Abundant illustrations and tables deliver essential information at a glance. Plus a convenient companion website features the fully searchable text with all references linked to PubMed.

Look inside and discover…
* Fully revised and updated content reflects the latest advances in the field.
* Current insights enhance readers' understanding of immune system function
* Unique approach bridges the gap between basic immunology and the disease process.
* Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment.
* Abundant illustrations and tables deliver essential information at a glance.

PLUS…
A convenient companion website features the fully searchable text with all references linked to PubMed.
 

目錄
Section I. Introduction to Immunology
1 The Immune System William E. Paul
2 History of Immunology Steven Greenberg
Section II. Organization and Evolution of the Immune System
3 Lymphoid Tissues and Organs Eitan M. Akirav, Noelia Alonso-Gonzalez, Lucy A. Truman, and Nancy H. Ruddle
4 Evolution of the Immune System Martin F. Flajnik
Section III. Immunoglobulins and B Lymphocytes
5 Immunoglobulins: Structure and Function Harry W. Schroeder
6 Immunoglobulins: Molecular Genetics Edward E. Max and Sebastian Fugmann
7 Antigen-Antibody Reactions Jay A. Berzofsky and Ira Berkower
8 B Lymphocyte Development Richard R. Hardy
9 B Lymphocyte Receptors, Signaling Mechanisms, and Activation Akanksha Chaturvedi, Angel Davey, Wanli Liu, Hae Won Sohn, and Susan K. Pierce
10 B Lymphocyte Responses Michael McHeyzer-Williams
Section IV. T Lymphocytes
11 T Lymphocyte Receptors Mark M. Davis
12 T Lymphocyte Signaling Mechanisms Takashi Saito
13 T Lymphocyte Developmental Biology Ellen V. Rothenberg and Ameya Champhekar
14 Peripheral T Lymphocyte Responses and Function Marc K. Jenkins
Section V. The Intersection of Innate and Adaptive Immunity
15 The Innate Immune System Luke A. J. O'Neill
16 Dendritic Cells Michel C. Nussenzweig
17 Natural Killer Cells Wayne M. Yokoyama
18 CD1d-restricted NKT Cells Albert S. Bendelac
19 Macrophages and Phagocytosis Siamon Gordon
20 Granulocytes and Mast Cells Patrizia Scapini, Nicola Tamassia, Carlo Pucillo, and Marco A. Cassatella
21 The Major Histocompatibility Complex and its Proteins David H. Margulies
22 Antigen Processing and Presentation Ted H. Hansen and Paul A. Roche
Section VI. Induction, Regulation, and Effector Functions of the Immune Response
23 Immunogenicity and Antigen Structure Jay A. Berzofsky
24 Fc Receptors and Their Role in Immune Regulation and Inflammation Jeffrey V. Ravetch and Falk Nimmerjahn
25 Type I Cytokines and Interferons Warren J. Leonard
26 Interleukin-1 Family Cytokines Charles A. Dinarello and Mihai G. Netea
27 TNF-related Cytokines in Immunity Carl F. Ware
28 Chemokines Philip M. Murphy
29 Helper T Cell Differentiation and Plasticity John J. O'Shea
30 Programmed Cell Death Andrew L. Snow and Michael J. Lenardo
31 Immunological Memory Shane Crotty, Susan M. Kaech, and Stephen P. Schoenberger
32 Immunological Tolerance Pamela S. Ohashi
33 Regulatory/Suppressor T Cells Ethan M. Shevach
34 Mucosal Immunity and Microbiome Yasmine Belkaid
35 Neurophysiological Reflex Mechanisms in Immunology Chavan and Kevin J. Tracey
36 Complement B. Paul Morgan
37 Cell-mediated Cytotoxicity Judy Lieberman
Section VII. Immunity to Infectious Agents
38 The Immune Response to Parasites Thomas A. Wynne, David L. Sacks, Alan Sher, and Eleanor M. Riley
39 Immunity to Viruses Hildegund C.J. Ertl
40 Immunity to Intracellular Bacteria Anca Dorhoi, Stephen T. Reece, and Stefan H. E. Kaufmann
41 Immunity to Extracellular Bacteria Moon H. Nahm and Jannet Katz
42 Immunology of HIV Infection Bruce Walker
43 Vaccines Ennio De Gregorio, Ugo D'Oro, Sylvie Bertholet, and Rino Rappuoli
Section VIII. Immunologic Mechanisms in Disease
44 Organ-Specific Autoimmunity Ken T. Coppieters, Matthias G. von Herrath, and Dirk Homann
45 Allergy Marsha Wills-Karp
46 Transplantation Immunology Megan Sykes
47 Cancer Immunology Hans Schreiber
48 Inborn Errors of Immunity Jean-Laurent Casanova, Mary Ellen Conley, and Luigi D. Notarangelo